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The Evolving Psychopharmacology Of Major Depressive Disorder: Narrowing The Treatment Gap

Depression is a widespread condition estimated to affect millions of adults in the United States alone. Despite the significant burden associated with depression, only a fraction of patients are estimated to receive minimally adequate treatment. While there are a number of treatment options and guidelines for treatment strategies exist, depression continues to constitute a significant source of burden. There are several theories regarding the underlying pathology of depression which have implicated structural and functional changes in the brain and alterations …

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