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The Role Of NMDA Receptors In The Pathophysiology & Treatment Of Mood Disorders

Research Summary | March 16, 2016

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Key Messages Glutamate and the N-methyl-D-aspartate receptor (NMDAR) may play a role in the pathophysiology of mood disorders. Several lines of evidence support a role for NMDAR signaling in bipolar disorder (BPD) and major depressive disorder (MDD), including: altered levels of glutamate in patients with BPD and MDD, abnormal NMDAR gene expression and function in…

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