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The Metabolic Basis Of Cognitive Insight In Psychosis: A Positron Emission Tomography Study

Key Messages

Cognitive insight has a biological/anatomical basis that can be visualized with imaging technology such as Positron Emission Tomography (PET).
The authors used PET to study the extent to which there are anatomical/metabolic differences between psychotic patients with low versus high cognitive insight.
The group with low cognitive insight had reduced metabolism in posterior brain regions (occipito- temporo-insulo-parietal) and increased metabolism anterior structures (orbito-frontal) regions.

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