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Effects Of Brain-Derived Neurotrophic Factor & C-Reactive Protein On Cognitive Impairment In Schizophrenia: Existing Evidence

Cognitive impairment is a core feature of schizophrenia spectrum disorders, known to affect individuals even before their first episode of psychosis. Affected cognitive domains where impairment is considered a defining and virtually universal characteristic in schizophrenia include attention/vigilance, working memory, executive function, episodic memory, verbal memory, social cognition, and language.1 Other cognitive domains such as semantic memory, fear extinction, processing speed, visual memory, and procedural memory are also affected, though not evidenced at the same severity.1
While environmental and lifestyle factors …

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