The Difficult Lives Of Individuals With Bipolar Disorder: A Review Of Functional Outcomes & Their Implications For Treatment

Research Summary | May 17, 2017

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Key Messages

  • Despite receiving treatment focused on resolving manic or depressive symptoms, many patients with bipolar disorder (BD) may still demonstrate impaired psychosocial functioning.
  • The ability to fulfill expectations at work, home, and school and have quality interpersonal relationships may be more important to patients with BD and their families than syndromic outcomes.
  • Resolving depressive symptoms (including subsyndromal states) and persistent neurocognitive impairments is important for reducing functional impairments associated with BD.
  • Possible treatment interventions that may enhance function in patients with BD include aggressive mood stabilization and depression treatment, use of pharmacotherapies that target cognition, and adjunctive psychosocial interventions.

The following is a summary of Gitlin MJ, Miklowitz DJ. The difficult lives of individuals with bipolar disorder: a review of functional outcomes and their implications for treatment. J Affect Disord. 2017;209:147-154, which was developed independently of the article authors. Background Although patients with BD (including BD I and BD II) may remain functionally impaired after syndromic symptoms appear to…

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