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Cognitive Impairment In First-Episode Mania: A Systematic Review Of The Evidence In The Acute & Remission Phases Of The Illness

Key Messages

First-episode mania (FEM) is a crucial time in the disease course of bipolar disorder (BD) because several cognitive changes are thought to occur during this time. There is considerable debate on whether cognitive deficits are present in patients who are asymptomatic before occurrence of FEM and whether they continue to accumulate in patients who are in remission after experiencing FEM.
This systematic review examined cognitive functioning in FEM.
In this review, acute FEM patients (cognitive functioning measured during an acute episode …

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