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Clinical Relevance Of Fatigue As A Residual Symptom In Major Depressive Disorder

Research Summary | June 9, 2015

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Key Messages Fatigue is a common residual symptom of major depressive disorder (MDD) and may be an adverse prognostic indicator. Certain fatigue-specific measures have been shown to be reliable and sensitive tools for the measurement of residual fatigue in patients with depression. Although mechanisms are unknown, it has been postulated that norepinephrine, dopaminergic neurotransmission, and…

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